Seong-Hee Maria Ko


Sookmyung Womens University




Dr. Seong-Hee Maria Ko received her doctoral degree from Dept. of Food Science and Nutrition, Sookmyung Women's University, South Korea with a dissertation entitled "Effect of 8-hydroxydeoxyguanosine on obesity-associated metabolic changes in KKAy mice" in 2009 and received her mater degree from the same university with a dissertation entitled "A study of antioxidant action of some fruits and vegetables juices consumed commonly by Koreans” in 2003 and was instructed by Prof. Hyun-Sook Kim, Council member, International Union of Nutritional Science. She spent her junior researcher, senior researcher and post-doctor course in Dept. of Pharmacology, college of Medicine, Seoul National University, South Korea over 13 years under the instruction of Prof. Myung-Hee Chung. In 2007, she received the Seoul Science Fellowship from the Korean government and also was selected by the Korean government for Brain Korea 21 Scholarship in 2009.
Her main areas of interest are metabolism, oxidative stress, DNA repair, and immune function. She has published various of papers related to them and short details are as follows;

  • Involved in the metabolic disorder study of type 2 D.M and obesity in KKAy mice (type 2 diabetic obese mice)
  • Involved in the detection of urine 8-oxo- deoxyguanosine (8-OHdG) as an oxidative stress marker in diabetic rat using HPLC (high performance- liquid- chromatography)
  • Involved in the detection of neopterin, a marker of immune response, and 8-OH-dG, a marker of oxidative stress, correlate at high age as determined by automated simultaneous HPLC analysis of human urine
  • Involved in the study on the formation of 8-hydroxyguanine by gamma radiation cellular dysfunction, and role of repair enzyme (OGG1; 8-hydroxyguanine glycosylase) of oxidative DNA damage
  • Involved in comparison of the antioxidant activities of nine different fruits in human plasma performing the measurement of ROS level in human plasma
    Her review paper, “Menopause-Associated Lipid Metabolic Disorders and Foods Beneficial for Postmenopausal Women” was selected as the most top downloaded paper (January - March in 2020). She teaches ‘Nutrition and cancer” and ‘Biotechnology’ for doctoral students in Sookmyung Women's University and she is a head of Dept. of research and development, Ho-Youn Kim's internal medicine clinic for Arthritis Rheumatism. She is working on autoimmune diseases that come from cytokine imbalances for obese people.

She speaks Korean, Japanese, English and Spanish. Thus, she has served as a translator for the Raphael Clinic that is a medical volunteer institute which has free medical service for foreign immigrant workers and refugees in South Korea. She was a Gabriel Prize Winner that is awarded to outstanding volunteers who have served more than 100 times at the Raphael Clinic ( She loves to play the piano and the cello.

Area of Interests

  • Metabolism
  • Oxidative stress
  • DNA repair
  • Immune function